Lucid 170ml

Generic composition: Magaldrate 800mg and Simethicone 100mg

Therapeutic category

• Antacid

Dosage forms available

• LUCID gel suspension 

Mechanism of action

These are basic substances, which neutralize gastric acid and raise pH of gastric contents. Peptic activity is indirectly reduced if the pH rises above 4. Antacids do not decrease acid production. Taken with meals antacids may act for at the most 2-3hrs.

Magaldrate is a hydrated complex of hydroxy magnesium aluminates which initially reacts with the gastric acid and releases Aluminium Hydroxide and Magnesium Hydroxide.  

Simethicone is a mixture of polydimethylsiloxane and silica gel. It is an anti-flatulent agent. It reduces surface tension and collapses the froth and allows the lower bubbles of froth collapse into the large bubbles and aids in expulsion. By defoaming the gastric juice, it decreases the incidence of GERD.

Uses

• Heart Burn
• Gastro esophageal reflux
• Dyspepsia
• Gastric and peptic ulcer

Dose

• Adults: 10-15ml 2-3 times a day with food
• Children: Half the adult dose

Side effects

Calcium carbonate antacids cause belching and constipation, magnesium salts can cause Diarrhea. By taking calcium and sodium carbonate together or with milk, there is risk of milk-alkali syndrome leading to headache, anorexia, weakness, abdominal discomfort and renal stones.

Contraindications

• Hypersensitivity to any component of the formulation

Drug interaction

• Magaldrate may negatively influence drugs like tetracyclines, benzodiazepines, and indomethacin.

• High doses or prolonged usage may lead to an increment of defecation and a reduction in feces consistence. 

• In some cases it can alter the functionality of the gastrointestinal tract, occasionally provoking constipation or diarrhea

Precautions

• Should be used with caution in renal impairment, pregnancy, lactation, elderly and children.
• Avoid taking any drug 2 hours before or after antacids to prevent interactions