Meryl Expectorant
Generic composition: Guaifenesin 100mg/5ml
General Introduction
Guaifenesin is categorized as an expectorant that acts by enhancing the output of phlegm (sputum) and bronchial secretions via decreasing the adhesiveness and surface tension of such material. Guaifenesin is extracted from the bark of Guaiac tree.
Therapeutic category
- Cough Expectorant
Dosage forms available
- MERYL Expectorant oral solutions
Mechanism of action
Guaifenesin is thought to act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi. It has been said to aid in the flow of respiratory tract secretions, allowing ciliary movement to carry the loosened secretions upward toward the pharynx.
Pharmacokinetics
- Guaifenesin is well absorbed from gastrointestinal tract after oral administration.
- It is metabolized hepatically and largely excreted via urine. Half life of Guaifenesin is approximately 1 hour.
Indications
Cough and chest congestion associated with:
- Common cold B
- Bronchitis
Dosage
- 2 years to 6 years: 2.5ml-5ml four hourly
- 6 years to 12 years: 5ml-10ml four hourly
- 12 years and older: 5ml-20ml four hourly
Side effects
- Dizziness
- Drowsiness
- Headache
- Nausea and vomiting
Contraindications
Hypersensitivity to Guaifenesin or its excipients.
Precautions
- Lactation
- Pregnancy