Lucotin

Generic composition: Luliconazole

General description

Luliconazole is a topical antifungal agent that acts by unknown mechanisms but is postulated to involve altering the synthesis of fungi cell membranes. It is an imidazole antifungal.

Therapeutic category

• Anti-fungal

Dosage forms available

• Luliconazole 1% Cream (Topical use)

Mechanism of action

The exact mechanism of action for luliconazole’s anti-fungal activity is still not known, but luliconazole is thought to inhibit the enzyme lanosterol demethylase. Lanosterol demethylase is needed for the synthesis of ergosterol, which is a major component of the fungus cell membranes.

Pharmacokinetics

About 99% plasma protein bound,

Uses

• Athlete’s foot (Tinea Pedis)
• Jock itch (Tinea Cruris)
• Ringworm (Tinea Corporis)
• Onychomycosis

Direction of use

• Apply once daily on the affected area for 7 to 14 days; two week for Tinea pedis and one weeks for Tinea corporis, Tinea cruris; treatment may prolong depending upon the clinical condition.

Side effects

Less common: Itchiness, redness and sensitivity around the area of use.

 Precautions

• Pregnancy and Lactation
• Luliconazole cream is for external use only. Do not let luliconazole get into your eyes, nose, or mouth, and do not swallow it. Do not use luliconazole cream in the vaginal area. Improper use may cause skin erosion.

Contraindications

Hypersensitivity to Luliconazole or its excipients.